Dysregulation of intracellular redox homeostasis by the SARS-CoV-2 ORF6 protein
This balance is crucial for protecting cells against oxidative damage
Without the gluta-thionylation, P-SOH groups may be further oxidized resulting in protein deactivation [42]
27 (15): p
The study by Honda et al., conducted in 2017, was an open-label, single-arm, multicentre pilot study that evaluated the therapeutic effect of oral glutathione administration (300 mg/day) in patients with NAFLD through the evolution of biochemical indices (ALT) and liver fat levels assessed by VCTE (79)
[DOI: 10.1038/modpathol.3800247] [DOI] [PMC free article] [PubMed] [Google Scholar] 30.Hoste EAJ, Roosens CDVK, Bracke S, Decruyenaere JMA, Benoit DD, Vandewoude KHDK, Colardyn FA